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Not every modern human has the same set of Neanderthal DNA, however; different people will, by chance, have inherited different fragments. But there are also some areas, termed "Neanderthal deserts," where none of the Neanderthal DNA seems to have persisted. Notably, the largest Neanderthal desert is the entire X chromosome, raising questions about whether this reflects the evolutionary fitness of genes there or mating preferences.

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The Test PLA extends this idea further. It operates asynchronously with respect to the sequencer. After a protection test fires, the PLA needs time to evaluate and produce its redirect address. Instead of stalling, the 386 allows the next three micro-instructions to execute before the redirect takes effect -- and the microcode is carefully written to use these delay slots productively. This is tremendously confusing when reading the microcode for the first time (huge credit to the disassembly work by reenigne). But Intel did it for performance.